Othertissue
L-Glutamine
2ATP
NAD(P)H
Glutamatedehydrogenase(liver mito)
α-Ketoglutarate
Oxaloacetate
L-Glutamate
AMP
Ornithine
CO2
Acetyl-CoA
Carbamoylphosphate
AlanineAmino-transferase
Pyruvate
Mito matrix
Cytosol
Glucose
NAD(P)+
Ornithinetranscarbamoylase
Malate
Liver mitomatrix
Citrulline
Glutaminesynthetase
Pi
PLP
Argininosuccinatelyase
Arginase
NH4+
N-Acetylglutamatesynthase
Other tissue
Aspartate
Glu
Malate-aspartate shuttle
Alanine
γ-Glutamylphosphate
Aminotransferase
ATP
In muscle
α-Keto acid
AlanineAminotransferase
Glutamate
Argininosuccinatesynthetase
L-Amino acid
Carbamoylphosphatesynthetase I
Arginine
Citric acidcycle
PPi
Aspartate-argininosuccinate shuntfor citric acid cycle
Argininosuccinate
Free
Fumarate
From ingested protein
2ADP
liver cytosol
Citrullyl-AMPintermediate
N-Acetylglutamate
Ureacycle
Glutaminase(liver mito)
Urea
ADP
H2O
