Assessed for eligibility(n=250)
Did not complete 6-week follow-up: Lost to follow up (n=5) Withdraw consent (n=2) Protocol deviation (n=2)
Complete 6-week follow-up(n=115)
Randomized(n=245)
Excluded (n=5): Random envelope lost (n=3) Exclusion criteria (n=2)
Did not complete 6-week follow-up: Lost to follow up (n=5) Protocol deviation (n=1)
mITT population (n=124)Safety population (n=124)
SSRIs(n=124)
mITT population (n=121)Safety population (n=121)
SSRIs+Tandospirone(n=121)
