基础实验流程图

Electron microscopy

synaptophysin

(pBCCAO)CCH

open-field test

vehicle control

Synaptic function

sham control

adult male Sprague-Dawley rats

 synaptophysin

Morris Water Maze

memantineintervention

behavioral test

Immunofluorescence

synaptic funciton

synaptic cleftsynaptic density

ALBspace learning & memorywork memory

western blot