442 Duplicate records excluded
3111 Records identified thro- ugh database searching
2669 Records screened
2587 Records excluded 2187 Not included CAD 252 About CAD algorithms 63 Review records 38 Not included lung CT scans 28 Case study 11 Records about animal expriments 8 Included cancer staging only
69 Records excluded 27 Not included CAD 18 About CAD algorithms 15 Included cancer staging only 9 Others
13 Studies included in systematic analysis
82 Full-text articles assessed for eligibility
