Excluded: Without mutation (n=158) Non-EGFR mutation (n=68)
Initial treatment non-squamous NSCLC patients (n=144)
NSCLC patients carrying EGFR mutation (n=224)
NSCLC patients tested by NGS in Second Affiliated Hospital of Nanchang University (n=450)
Initial treatment non-squamous NSCLC patients with EGFR mutation (n=117)
Excluded: Not Stage IV (n=18) Untreated (n=9)
Excluded: Non-initial treatment (n=76) squamous cell carcinoma(n=4)
