CYTOSKELETON

Cytoskeleton

don't need GTP or ATP

Assembly process

keratin

Affecting drugs

Forming a complete support grid system in the cell 

Provide mechanical strength support for cells

Supporting cells

Substence Transport

子主题

Cell differentiation

Singaling

Function

Intermembrane filament/IF

Kaetagener

Wiskott-Aldrich

EBS

Disease concerning

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α-tubulin

β-tubulin

Types

tubulin

① GTP-β tubulin binding to GTP has a strong affinity with the end of microtubule and is easy to be added to form straight fibrils;

③ The assembly of microtubules mainly takes place at the positive electrode.

promote polymerization

paclitaxel

block polymerization

colchicine

Maintenance of cell morphology by scaffold action

Involved in the transport of intracellular substances

Maintain location and distribution of organelles

Elements that make up the motion of cilia and flagell

Formation of spindle and the movement of chromosome

Microtubule/MT

Composition and morphology of microfilaments

Nucleation phase

Extension phase

Equilibrium phase

Phalloidal cyclic peptide

Cytochalasin

To form a scaffold for cells and maintain their  morphology

Participate in muscle contraction

Participate in cell division to form a contractile loop (actin and troponin)

cytosis

Metamorphosis motion

phagocytosis

Participate in cell movement

Substance Transport

Signaling

Microfilament/MF